UniProt, the Universal Protein Resource, serves as a comprehensive repository for protein sequence and function data. It integrates information from Swiss-Prot, TrEMBL, and PIR to provide a centralized resource for researchers.

On another note, a quantitative LC-MS/MS analysis kit for total homocysteine in human plasma samples has been developed. Homocysteine, a non-protein amino acid, is synthesized from methionine and can be converted into methionine or cysteine with the help of B-vitamins. Elevated plasma homocysteine levels have been linked to cardiovascular and venous diseases, often due to genetic mutations or deficiencies in essential B vitamins. Factors such as age, smoking, hypothyroidism, poor diet, chronic kidney disease, and renal disease can influence homocysteine levels.

Traditionally, homocysteine levels have been measured using methods such as HPLC and immunoassays. However, liquid chromatography combined with mass spectrometry (LC-MS/MS) systems have become increasingly popular due to their shorter analysis run times, reduced labor costs, and enhanced reliability and sensitivity. The Zivak Total Plasma Homocysteine LC-MS/MS Analysis Kit offers rapid, sensitive, and reliable quantitative detection of total homocysteine concentrations in human plasma samples, providing results in just 5 minutes with minimal sample preparation. The kit's main methods and procedures adhere to standards such as EN ISO 13485 and 98/79/EC.